Heredity B/Designer Genes C

[Tailsfan101]

List the three steps in post-transcriptional modification, and, if applicable, which end of the mRNA is altered by them.

1. Splicing of all the introns 2. Polyadenylation on the 3' end 3. Adding of the 5' cap

All correct, your turn!

[reninkidney]

1. What role does the Shine-Dalgarno Sequence play in the initiation of translation?



2. What type of inheritance does this pedigree show?

3. If individuals I-1 and I-2 had another son, what is the chance that he would have the disease?

[EwwPhysics]

1. What role does the Shine-Dalgarno Sequence play in the initiation of translation?



2. What type of inheritance does this pedigree show?

3. If individuals I-1 and I-2 had another son, what is the chance that he would have the disease?

1.[hide]It helps align the ribosome with the start codon in translation[/hide]
2. [hide] Uhm unless I'm being really stupid it could be either autosomal recessive or X-linked recessive.. though based on your third question I assume you mean it to be X-linked?[/hide]
3 [hide]100% if it's X-linked... 50% if not[/hide]

[EwwPhysics]

oops sorry that it didn't hide >w<

[Tailsfan101]

oops sorry that it didn't hide >w<

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[EwwPhysics]

oops sorry that it didn't hide >w<

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Thanks!

[reninkidney]

1. What is the difference between euchromatin and heterochromatin?
2. What is the difference between positive & negative regulation of the cell cycle?
3. What is telomerase?

[EwwPhysics]

1. What is the difference between euchromatin and heterochromatin?
2. What is the difference between positive & negative regulation of the cell cycle?
3. What is telomerase?

1. Euchromatin is transcribed much more often and is more common, more lightly packed. Heterochromatin is more condensed and is usually used for centromeres and telomeres.
2. In positive regulation, cyclin complexes cause the cell cycle to progress but in negative regulation, they halt the cell cycle (sorry if this sounds copied and pasted, it honestly probably is because I took it from my cheat sheet >w<)
3. It is an enzyme that lengthens telomeric DNA by adding repetitive nucleotide sequences to the ends of chromosomes, which allows them to avoid the Hayflick limit (stops them from having a limited number of divisions because of lost material at the telomeres)

[reninkidney]

1. What is the difference between euchromatin and heterochromatin?
2. What is the difference between positive & negative regulation of the cell cycle?
3. What is telomerase?

1. Euchromatin is transcribed much more often and is more common, more lightly packed. Heterochromatin is more condensed and is usually used for centromeres and telomeres.
2. In positive regulation, cyclin complexes cause the cell cycle to progress but in negative regulation, they halt the cell cycle (sorry if this sounds copied and pasted, it honestly probably is because I took it from my cheat sheet >w<)
3. It is an enzyme that lengthens telomeric DNA by adding repetitive nucleotide sequences to the ends of chromosomes, which allows them to avoid the Hayflick limit (stops them from having a limited number of divisions because of lost material at the telomeres)

All correct! Your turn!

[EwwPhysics]

1. What are nucleosomes?
2. Why does X inactivation occur?
3. What are some common applications of PCR?
4. Briefly explain mosaicism